Review Article on Applying Tumor Genotyping and New Clinical Approaches to the Management of Colorectal Cancer


Abdominal metastases from colorectal cancer: intraperitoneal therapy

Hamza Guend, Sunil Patel, Garrett M. Nash

Abstract

Patients with peritoneal metastasis from colorectal cancer represent a distinct subset with regional disease rather than systemic disease. They often have poorer survival outcomes with systemic chemotherapy. Optimal cytoreductive surgery and intraperitoneal chemotherapy (IPC) offers such patients a more directed therapy with improved survival. In this review, we discuss the diagnosis, evaluation and classification, as well as rational for treatment of peritoneal carcinomatosis (PC) secondary to colorectal cancer.

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